Our mission is to develop a safe, effective and reliable solution to treat spinal cord injury, for every patient. NeuroPair’s patented treatment approach can magnetically generate a shape-conforming scaffold in situ – directly within the injury site – for the regeneration of neurons that were damaged due to a spinal cord injury (SCI). Injured neurons need to be given the opportunity to regenerate, get protection from scar formation, penetrate already-formed scar tissue, and be guided in the right direction to be able to reconnect and preserve and restore lost function.
Spinal cord injury includes very different types of injury patterns that typically require different surgical approaches for damage control, stabilization and possible treatment. Because shape and condition of SCIs vary so much, one-size-fits-all approaches are unlikely to succeed. SCIs are also more complex compared to emergencies such as heart attacks or strokes with established treatments, and therefore require multimodality therapeutic approaches. Optimally, there is spinal cord decompression surgery within 24 hours of injury to give the patient a chance of at least partial recovery. A successful treatment should also be compatible with other treatment options, such as stem cells, neuroprotective and bioactive factors, and epidural stimulation.
To the surgeon, the nature of the injury (concussion, crush, transection, partial, complete, spinal position, dorsal, ventral etc.) and the shape and condition of the injury site in both acute and chronic SCI present very differently for each case – “Every injury is different”. A recovery that exceeds any one that is expected spontaneously requires new axonal growth and circuit formation.
For that to happen, a favorable biophysical environment is needed, one that is compatible with other treatment options that the surgeon considers best given the individual situation and prognosis of the patient. Chances for functional recovery increase greatly if such an environment can be established rapidly after an injury has occurred, which is what NeuroPair’s technology can provide. NeuroPair’s initial focus however is on a treatment for subacute injuries, when a patient has been stabilized. Chances for any functional recovery are considered low at that time, but the injury site is still susceptible to being remodeled, and the functional reconnection of severed neurons is still possible, given the right conditions.
Fibermag® is a single-use, two-component injectable formulation for Research Use Only. Magnetically generated from nanoparticles, our patented FiberguidesTM align into stable yet flexible scaffolds that can penetrate debris and extend across even irregularly shaped spaces. We assist customers in selecting and functionalizing the right type of FiberguidesTM for their desired applications.
For additional information, refer to Instructions for Use.
The Fibermag® RUO kit and current other NeuroPair products and services are not intended to diagnose, treat, cure, or prevent any disease.